The EU-funded MULTI-ACT project set out with an ambitious and forward-looking goal: to increase the societal impact of health research, particularly in the field of brain diseases, by developing a new, inclusive, and co-accountable model of research governance. Recognising that traditional approaches to research evaluation often fall short in capturing outcomes that matter to patients and society, MULTI-ACT aimed to transform the way health research is defined, conducted, and assessed in Europe.
At its core, MULTI-ACT created and piloted a comprehensive governance framework designed to enable the effective cooperation of multiple stakeholders—including patients and patient organizations, academic institutions, public bodies, and private sector actors. This model goes beyond consultation, actively engaging stakeholders in defining research priorities, co-designing projects, and evaluating results through a shared, mission-driven agenda.
One of the project’s major contributions was the development of new metrics and indicators for assessing the value and impact of research. These metrics are not limited to scientific outputs, but include societal, ethical, and patient-relevant dimensions, ensuring that research outcomes reflect what truly matters to those affected by brain diseases.
The MULTI-ACT framework is particularly suited to multi-stakeholder research initiatives led by Research Funding and Performing Organizations (RFPOs)—whether they are already part of established alliances or looking to adopt a collaborative, co-accountable approach to health research. The project offers practical tools and guidance to help these organizations align around a common mission and measure their progress effectively.
Throughout its implementation (from May 2018 to May 2021), MULTI-ACT worked in close collaboration with a wide range of stakeholders across Europe. This included patients as equal partners, contributing their lived experience and perspectives to shape more meaningful research. The result is a scalable and flexible model that can be applied beyond brain research to other complex health challenges, helping ensure that research serves the public good more effectively.
MULTI-ACT received funding from the European Union’s Horizon 2020 Research and Innovation Programme under Grant Agreement No. 787570, and it has left a legacy of tools, guidelines, and practical knowledge that continue to inspire more inclusive and impactful research governance in Europe.
as third party of FISM (Italian Multiple Sclerosis Foundation – WP1 & WP9 Leader), coordinator of the Project, is responsible for the overall management of the project.
